Mine has a Shilean barrel and is freaking stupid accurate.Wasn't as accurate as I hoped (back when I thought Shilen barrels were the "be all end all") and the velocity just wasn't there. I have also become a big believer in cartridges formed from the .404 Jeffrey - 300 RUM, Edge, 28N, SAUMs, etc. For whatever reason, they all seem to be very accurate - kind of like the .308 Win case.
However I have only used 140's so far and I stopped at the first big node on my ladder and it is running 3535. I didn't mess with seating depth, set my depth to run through the magazine and then started my ladder.