I am a fan of getting the best shot placement that I can . That is why I study how to make my rifle shoot it's best and then study how to load my ammo so that it fires and groups the best that it can in my rifle . I also think it is my responsibility to treat the animal with respect and make as good a kill shot as I can . A good clean kill is my main concern . With the advancement in bullets that has come about by the increased interest in long range shooting and hunting in the last few years knowing where your bullet will impact , if you have done your part, shouldn't be a problem . We have access to wind meters , range finders , angle finders ect. so that if we don't get excited and forget to use these or we don't get in to a situation where we rush things shot placement should be good and we will not feel the need for larger then needed calibers to compensate for shot placement . We all have a responsibility to the animals we hunt to study and fine out for ourselves what we feel to be our own rifle caliber of choice for the hunting we do . The day of everyone only having one rifle for all hunting shouldn't be a problem these days . Me saying what my preference for this or that is just that my preference based on my study of the intended use and hopeful out come . I believe that to be the reason a lot of people come to this site to study others thoughts and figure out what they want to try for themselves without spending a lot of money and time to get it right . We want to learn from the experience of others and be able to trust in that experience . I personally am glad that we choices of calibers ect. I wouldn't want for all of us to still be using 45-70 .