I've killed deer with .243 win, 6mm rem, .250 savage, 6.5x55, .270 win, 284 win, .300 savage, 30/06, 300 win mag, and 7.7 japanese......I have to say my two favorite rifles are a very light weight .284 Win, and .250 savage on a Swedish mauser action....Its hard to have just one favorite!