Over the years I've seen a whole pile of deer shot in the head illegally (here in TN) with a 22lr, and I've never seen one drop. Coyotes ate them all eventually. I had a "buddy" that told me how he always killed them that way, and I watched him wound 3 does in one weekend. He hit all 3, I saw it happen, and all 3 ran off without any blood trail to follow, and they were never recovered. I worked for a farmer that used to have a depredation permit to kill deer in his fields year round, and I've seen him shoot a dozen or more over a couple of years with a 22lr. He would try to make head shots, but he shot some of them in the lungs, and I never saw one of those deer die. Every single one disappeared into the woods. And finally, my own story: when I was an eager 14 year old alone in the woods squirrel hunting with my 22lr, I had a doe walk right to me, like 20y, and I opened up on her with my 22lr. I probably hit her in the lung area 5 times or more at point blank range. I pursued the tiny drops of blood for miles until I couldn't find anymore blood, and never found her. So, I'm far from calling you a liar, however, I think shooting an animal bigger than a raccoon with a 22lr, unless it is in a trap or you are at point blank range harvesting a domestic animal is a really bad idea. I've seen coyotes run off after taking a solid .223 or a .204 round to the chest, and if they get to 40lbs they are a monster. I think, (this is my opinion, based on the massive number of deer I've shot and seen killed), that you need a relatively fast 6mm cartridge or bigger to responsibly kill whitetail. Sure, you can kill them with a 22lr, sure, you can kill them with a .223, but I don't care what anyone says because I've seen it too many times, you will lose some. When they allowed the .223 to be used for whitetail here in TN and everybody with an ar15 was out there winging them, the coyotes ate good. I hunt with enough gun so that I have the ability to reach the vitals on any reasonable angle. I want to know that my bullet isn't going to spall on the shoulder and do no real damage, and while bullet selection is key, nothing beats energy. I want to be able to go straight through the shoulder socket and kill, in case that is the only shot I have.