I've used the 135 SMK a fair bit on small big game (deer,antelope) and yotes and such. Farthest I shot game with the bullet is just a bit over 500 and it put the muley down quickly with a behind the front shot.
For powders I'd suggest the normal's for a bullet of this weight in a .270. Not sure which your gun will like but I'd give whatever of the following you can get your paws on. H4831, one of the 4350's, R22, R17, 7828. I'd think you can get one of these to perk.
For what it's worth, I've used the 135 SMK, the 140 SGK and the 140 SHP in several 270's over the years. In all 3 the SHP was the most accurate, followed by the SGK then the SMK. But in reality I had good accuracy with all of the above! All 3 are very yote capable!