The larger the bore size, the more surface area for pressure to act on the base of the bullet. So, say you compare a 300 PRC to a 7-300 PRC, the 300 will push the same weight bullet faster than the 7 bore can. When we talk about efficiency, we are usually talking about what velocity we can get for a certain amount of powder. Basically the bigger the case the less efficient it will be. If a case design handles higher pressures, it will be more efficient. Efficiency is tied to accuracy. There are certain case size "limits" for the very best accuracy. In competition this is quite obvious when you look at the consistent winners. When it comes to the 7 and 30, the biggest case sizes that win consistently are the 284 (with a handful of 7 saums) and 300 wsm. But those cases do not always give the performance we want for hunting, so we trade a little bit of raw accuracy to gain performance.