I think the Nosler Partitions are very effective hunting bullets. My dad shot a New Hampshire bull using my 300 RUM and a 180 gr Partition. The bull didn't take a step. Of course, the Idaho bull he shot a few years earlier with his 300 WM and a 180 gr Core-Lokt dropped in its tracks, too. My only gripes with Partition Spitzers are the relatively low ballistic coefficient and nose deformity in the magazine. However, neither matters at the ranges most of my shooting has been.
If I ever draw another moose tag and decide to carry a 30 caliber magnum, I will probably use either a Barnes LRX, a Hammer Hunter, a Nosler Partition, or a Swift A-Frame.