I am assuming you have never killed much with a 375? velocity, energy etc have nothing to do with killing power. the sheer Diameter of the 375 in itself is a whole new class of killing. Maybe HarperC will chime in. I recoveres a 270 TSX from the hill side once and the mushroom measured .980 ... 1" hole is hard to argue with. paper numbers and real world results are 2 different things
See Mike assumptions are dangerous!! I've gone up to the big 458's think that big bore diameter kills consistently across the board. I've dug piles of 1" diameter slugs out of the dirt and pine trees even elk only to find that did not kill like lightning at range or on some game.
Lets romp on a 350 gr bullet from a big 458, I've absolutely violently crushed elk at hundreds of yards but I've watch better than a dozen deer take a hit like a rock stars and run and run a heck of a long ways, the last animal I killed with it was a doe mule deer, shot her facing me under a 100 yards but she did not have the mass to open the bullet and my buddy shot her up the spine just before she cleared the next ridge. Push the ranges on it and you start just knocking holes through stuff, ya it kills them it's not the mine blowing smack down that was going on when the bullet opened!
The 375 Cheytac with solids will do quite a number on an elk at closer range and the bullet tumbles but push it out and the bullet does not tumble and they run, I know more than one guy who went back to the 338's from the 375 after a while of hunting. I also have a little lathe project to do that involves making 375 cal TSX open better on elk for my uncle's 375 H&H because he's not happy with how far elk shot behind the shoulder are running, through the shoulders brown is down but you don't always do that when their running through the timber.
It's not just on paper Mike, I think the CEB's bring something to the table because they will open at longer ranges or if Kirby can get tips in the 350 SMK but if the shear diameter of the 375 was all that is needed then everyone and their dog would not be trying to make a better long range bullet for them!