First of all welcome to the sport and hobby! I started out many years ago and my first cal to load was the good ol' 30-06, as my teacher in the military said it was a great cal to learn the ropes with.
A couple of questions: first what kind of seater die are you using, and second how are you crimping? Let me explain...
All dies are not created equal. It makes less difference which full-length sizer you are using, as most brands are reasonably "good enough." But for seating there are two big questions - is the die holding the bullet in proper alignment with the case neck while seating? Poor alignment leads to inconsistent neck tension, lateral runout, etc. In other words, it degrades accuracy. Ditto the proper seating stem...if it does not match the bullet you are seating then the same problems occur plus possible tip deformation.
Next up, crimping. Many of the more affordable seating dies include a crimping ring and instruct you to seat and crimp in one operation. Resist this! Seat first, then crimp in a separate operation. And of course make sure you are using the proper form of crimp. Roll crimp into a cannelure, taper or use a Lee factory crimped if no cannelure is present on your chosen pill. I have seen several new reloaders get this wrong and the results were predictable.
Get a Forster Comp seater and a Lee fac crimper and you will probably see some improvement. Assuming you trim brass to tight specs say plus/minus .0015" and crimp properly to even out the neck tension, your rounds should start with a consistent release pressure. From there you can tweak the powder charge up or down until you find the sweet spot for your launcher.
FYI 4350 is a good choice for the '06 across the spectrum of bullet weights. Varget also does well, but I recommend sticking to one powder per bullet choice until you learn the tricks of the trade. Load a given brass/bullet/primer/powder combo to manufacturer's recommended overall length, tweaking powder charge until you can consistently get best sub-moa groups (3 shots) at 100 yards. Then take that load and play around with seating depth in increments of .005" and you'll maximize the accuracy of that combo.