Let me preface this by saying that I am primarily an archery guy and the only reason a rifle gets taken out if the safe for hunting is if I need to fill a tag I wasn't able to with a bow. The rifle of choice for that is a tikka in .308, because it's easy. A 130gd ttsx will kill anything I would point it at, was easy to develop a load for, and if I need factory ammo I know I can find it. There are probably a hundred better calibers that I could use for whitetail out to 400 (I am the limiting factor), and the deer wouldn't know the difference