I bought 3 different pack frames before finally buying a Kuiu pack. The others were fine under 60lbs and under 3 miles, but got really uncomfortable after that, and gave me some serious bruises. Bought the Kuiu, and its super comfortable and adjustable for your specific shape/ dimensions.
Got the Icon suspension and the Ultra 4000 bag, which is plenty for 4-5 days for me. I pack the meat between the pack and frame.
Few hundred training miles with 60-100lb loads, all super comfortable, even after 6-7 miles at a stretch.
Shot a whitetail last year, and didnt feel like breaking it down... just gutted it and strapped it to the pack, head, hide and all. Weighed it back home at 136lbs.(smaller buck during archery season) Hiking the hills back to the truck wasnt fun for my legs, but the pack handled it no issue.