After much reading on this unicorn powder I tried it in my 243AI with 105s. With Re22, I was able to get 3250 if I was willing to beat up my brass; I ended up at 3200 to not destroy my cases. 3280 would have been one use only.
With Re26, I am essentially getting 80-100 fps with the same effects on the case. So I can shoot about 3280 with the same brass result as 3200 with Re22.
Compared to the unicorn claims this is a modest difference. Earlier claims in this thread are 3380 for 243AI, mine is a 24" barrel, I hope they are shooting much longer. I guarantee this would blow primers in my rifle. But, this is a significant enough difference that I will transition to Re26 as my routine load.