The big to-do about shooting lead bullets out of the polygonal barrels is that, like any other barrel, if the leading gets bad, the pressures of even standard loads can go way up. The simple cure is to shoot a few rounds, maybe 20 or so, then check the barrel carefully for leading. Some barrels just lead more than others, simple fact of life. If yours leads badly (and you cannot tell by shooting just one round) then you will either have to give up on the lead or polish the barrel with something like NECO system or the Tubb system. I have not used the Tubb system but the NECO system works if you follow the directions and do it right. It will have no effect (usually... and if it does it will likely be positive) on accuracy but the barrel will very likely reduce or completely stop the leading. If it still leads a little, continue with the finest polishing rounds until it stops. I've had very good luck with the NECO system and I don't suspect the Tubb system to be any different.
The number one thing about shooting plain lead bullets out of your Glock is good old common sense! Don't shoot a couple of rounds of lead, call it good, then blast another 500 rounds if the stuff down range! Check the barrel every 100 rounds or so to be sure. Last is, pop off 10 rounds of stiffly loaded 180 or 200 gr. jacketed rounds after shooting lead bullets (and checking the bore for lead build up. If there's just a little lead the jacketed rounds will, if not actually blow it out, will smooth it down so that there are no lumps that could cause a pressure spike! Again, use your head! If there really are visible lumps of lead in the barrel you didn't check often enough and will have to scrub the lead out. I've heard very good things about Birchwood Casey's lead remover cloth but haven't actually used them... yet! They're on my list. Otherwise, JB Bore cleaner works wonders. Just be prepared, it is labor intensive! Do NOT resort to using bronze brushes and a drill motor. Just don't do it. Removing lead is the *only* time I can recommend pushing and pulling a bronze brush all the through a barrel. If just normal cleaning, a single pass, from chamber to muzzle, is the only way to clean a barrel! Patches only go one way, once. Then they get tossed. Unless you don't worry at all about the long term health of your barrel. If you want your kids and probably grand kids to be able to shoot your pistol as well as you do, take good care of it and pass along the good habits to your descendents and the gun and barrel will last until the govt comes to get them!
If you don't even think of such things, go for the drill motor and beach sand to clean your barrel. Just don't whine to me when you pistol goes from shooting 1" groups at 10 yards to 4" groups!
Cheers,
crkckr