While a tight throat is good IMO, it doesn't actually center WHERE the chambered bullet is pointing.
Look at the length of throat -vs- length of loaded ammo. That throat is a small fulcrum in this respect, and it is also a pressure point when ammo runout is high.
Pressure points, anywhere in the shooting system, are bad things.
But, the reason the throat doesn't hurt much as a pressure point(until extreme) -is because it's just a small fulcrum, about which the chambered ammo can settle into alignment, given clearance to do so.
The whole thing with runout is a loop. Either a big loop (with big clearances), or a small loop (with small clearances).
Big clearances lead to big runout, but it's ok to a point because of big clearances.
Small clearances lead to small runout, which is good because larger runout would shoot bad with small clearances.
Your sizing plan should account for this.