Still...
Two basic issues..
#1 platform (weapon type). Revolver or Auto to be used.
#2 load, bullet, weight, material..lead... .hardcast...jacketed....soft point
As to #2, African hunters have proven the value of solids. They penetrate straight, break bones and reach vitals. I would contend griz are more like African buff than lions or leopards and in most cases we are better off with hardcast solids for large bears. Why is this so difficult to grasp or understand? A bullet, shoft lead, pure copper, lead and copper poor even soft points driven at pistol velocities don't penetrate as reliably as hardcast lead.
Point#1. Auto pistols provide increased rates of fire, we have all seen the armchair comando rip a full mag in a second or two....so what! How accurate can one be? Apologies to trained operators reading this but we mortals will not get the performance differentiators trained pros get from autos. We will be lucky to get one round off when needed in an attack. Look at the bear incident reports from the last few years...most identify that shooters have already been in physical contact while trying to present a pistol and fire effectively. Cocking a S/A revolver is a step most would be challenged with? Racking a round into the chamber of an auto while being chewed on is darn near impossible.
This post keeps going back to bullet weight, design and powder charge? Would it not be more wise to think about the delivery platform first and then think about what we know to work? Thinking about how to enhance the 10mm it's fun but it's not going to pay off no matter what after market barrel is used.