There's nothing wrong with them, but they're not on par with an FA. The fit and finish of a single six isn't comparable to an FA. FA's are more accurate. The lockup is incredibly tight. You don't get much tougher than a solid stainless frame designed for 454 Casull. Reliability is more or less equal between the two. Aside from misfires die to bad ammo neither has ever given me problems. You have more options in barrel length, frame size, and sights with a FA. If you want to use a scope you just unscrew the rear sight and screw a mount in the same holes. 22 mag cylinders are available from FA.
Of course, all that comes at a cost. A used FA runs around $2000, and a new one runs about $3000.