I've seen many Bulls require a second shot to put them down quickly.
Aside from the bull I shot through the lungs last fall, I've had several more hit center lung make serious ground before bedding down.
One was alive an hour after I put a 147 directly through both lungs.
I've also seen some chases with shoulder shots but literally zero got away, and nearly all bedded much sooner than bulls I've seen that were lung shot.
All were with eldx, eldm, and Bergers
Also I'm talking bulls not cows, for anyone who really hunts elk its common knowledge that cows die waaaaaay easier.