Best All Around Caliber for Whitetail and Mule Deer?

If you dont mind sharing, What bullet are you using, and what distances? Sounds like some really good data!
I've taken over 500 whitetails, a 176 & 184" mule deer, Coues, Carmen Mtn. whitetail, and 120" blacktail with my 6.5/.284 XP-100 handgun, plus a whole lot of African game.
This round kills way beyond what you would expect with much less recoil than the bigger rounds.
 
Best all-around? That means the best combination of flat trajectory, moderate recoil, and effective terminal ballistics, from point-blank range to at least 500 yards? Eastern whitetails in deep woods or western mulies in the mountains?

The jack-of-all-trades is the master of none. Lots of good choices, at either extreme or as compromise cartridges. Within 400 yards anything from a .243 to an '06 will do fine. I have hunted the single shot straight wall deer season with a Miroku Low Wall .44 Magnum, whietails with a M70 .243 and '06, mulies with a .338.

Any reasonable cartridge and rifle will do, if you will do.
 
This is for deer only in western states . Never seen any mule deer running around on the east coast side of the USA. 😄 I have been torn between a 7mm mag, 270 win or a 300 RUM. Wanting opinions from those more familiar with the area out there. I know not one caliber or bullet covers it all. But I have long favored the 7mm mag with a 160 Nosler partition for most all conditions.
 

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