The two 4350's Hodgdon and IMR are not the same. They are close but not a match so do your development separately if using those two powders. I would just flip a coin, heads Hodgdon, tails IMR, and stick with that powder. Either are a good choice and in non-pandemic times both would be readily available.46 grains of 4350 with 139 interbonds is a great combo. Deadly on deer or bear. Couldn't get 120s NBT to group