TH - I just re-read your posts in this thread and found you are looking at a re-barrel, not a full build. That question answered.
The main problem with a proprietary cartridge is that you have ZERO control over if and when you can get a follow up barrel. Anything under heaven could happen to cut you off. Having you own reamer puts YOU in control. The performance may not be the same but it might not be much different.
Please also note that what Fred suggested was just one of many possible designs - different base-to-shoulder length and/or body taper, 40 degree vs 37 (resale issue for a potential buyer that "must" have 40), and all the possible tricks that can be applied in the throat area. If you are an FCSA member, ask for a Improved designs on the Members Only forum. The .50 Williams and Williams/Burtt 50 Improved come to mind. If you are not a member, you're long past the point to invest in a membership - and the resource pool that goes with it.
BTW, what is you application - FCSA (if so, check the regs on "improved" versions and what class that may drop you into), unlimited range (URSA), or?