If your really wanting to do this then my suggestion would be to stick with a maximum of 26 inch barrel for practical use even though you say you are not concerned with that. Before you or any of us build such an awesome rig, I would try to find the bullet in either 22 or 6mm that will hold up to the rotational speed and velocity then build based off that factor. I have been down this road as have a few others and from my past experience this will be one of the main issues. The bullet nose can also deform at those speeds causing issues farther down range. A 52-80 grain bullet traveling at 4200-5000 with a 26 inch or less barrel would be a very usable and fun round. Just my opinion for what it's worth.
As suggested before, have 2 barrels cut at the same time because I only got 620 rounds out of one of my Cheetah barrels. With some of the slower powders now and the blends, that may not be as pronounced now?