I have used several 25 cal and still do.
My first was/is a .257 Roberts shooting 75gr Hornady hp over IMR4064. Mostly coyotes, but a couple bobcat as well. I also tried the 60gr for the .25-20 out of it, as well as heavier ballistic tips. The 75gr Hornady was the go to for me. Shot Rockchucks by the truckload.
Out of the .25-06, I've used the same Hornady bullets, but also tried some Nosler BTs. Much the same as the .257R.
Also have a. 25 WSSM that was my father's, that I haven't really done much with. It's a Win Stealth II, so it's heavy, great over bags, and would be great for prairie dogs, but I'm not close to that kind of ground any more.