One of the reasons load data for 220 grain bullets in the 10 mm Semi auto are not common is the changes that have to be made to most pistols in order to function correctly.
The 180 and 200 grain bullets are the weights that most 10 mm auto's are designed for, plus they produce much more Muzzle energy and less recoil.
The muzzle energy for the 180 is 662 ft/lbs at max load. (1287 average max velocity)
The 200 grain bullets produce 610 ft/lbs at max load. (1172 avreage max velocity)
The 220 class bullets can only be pushed to 941 ft/sec without extensive modifications to the pistol and at these velocities only produce 433 ft/lbs of muzzle energy.
Maximum SAMMI pressure for the 10 mm is 37,500 Psi and the 950 ft/sec 220 grain load averages 36.000 Psi so you can't go much/any faster without pressures exceeding design.
For self defense, I would recommend jacketed bullets with a round nose or similar shaped hollow point for enhanced feeding. And past experience tells me that any cast bullets or gas check designs are not as dependable as jacketer designs.
The extra energy and dependability favors these Bullets in the 10 mm in my opinion.
For what its worth.
J E CUSTOM