I've killed a boxcar full of deer with a 30-06, over the course of 40 years.The .30-06 would be my favorite hands down. With that said, I had a rifle built in 2018 that I drank the Kool-Aid and had it chambered in 6.5 Creedmoor. It's now my doe patrol rifle. I've killed exactly 50 whitetail does at the time of this post with that 6.5 Creedmoor. Definitely not the best, but I've never felt like it didn't have enough to get the job done and well.