Have experience with an AR upper and a buddy has the bolt action Ruger American in 350 Legend.
Great experiences with the round in both rifles.
I have a Bear Creek Arsenal 16" upper, bought 2 CMMG magazines that were chambered for 350 Legend. No issues with failure to feed or firing.
Shot the 145gr FMJ, 150gr polymer tip ammo and the 180gr soft points, no issues with feeding or firing with any of this ammo out of my upper.
Really good accuracy out to 200 yds with the Winchester 180gr Deer Season ammo.
I couldn't be happier with performance on an economy upper.
This is 4 rounds at 100 yds.
Took this buck at 70 yds. He was trotting out of a draw.
3 shots at him, one took out his liver, another top of his heart and the 3rd wiped out his spine and he dropped like a pile of bricks. All were pass through shots on a nice sized Iowa buck.
My buddy who bought the Ruger American bolt rifle in 350 had similar experience.
Very good accuracy with the Winchester 150gr ammo. His 13 yo son took a doe at 125 yds. Stiff cross wind and he dropped her in her tracks with one shot.
In Midwest states (or wild hog country) this is a good option for those sensitive to shotgun, 45/70 or 450 recoil. I had a 450 Bushmaster last year that I hunted with but it was so loud (have ringing in my ears all ready) I was going to be deaf shooting that caliber. Even with ear pro in, bad deal. Lethal on deer though.
Hope this is helpful info.