I avoid the shoulder like the plague most of the time!! My number one reason is you average 8lbs of meat lose per hole to the shoulders, shoot through both and you loose 16 lbs of burger meat min.
Second, I deliberately shoot elk through the shoulder or neck at least a couple times with each bullet I test just so I know what I can get done with it and the 6.5 140 gr bullet will not always blow up a vertebra, you get some cracking or a hole drilled through it but not that blown up effect which will anchor and kill. If you shoot lower in the mid shoulder a 6.5 bullet simply won't penetrate to chest, I've had 30 cal magnums with hard bullets even fail there.
I HATE elk dropping in their tracks only to have them start to flop around and eventually get their legs back under them, I see this multiple times a year either from to light a bullet just hitting the spine but not breaking it or cutting the cord or shot placement going a little to high and blowing the top of the vertebra of. Then you have the elk that has a leg windmilling from a low shoulder hit with an inadequate bullet for the job.
If I do drop one, I'll sometimes just put a second round through them immediately through the lungs just to make sure I walk up on a dead elk, at a minimum I'm ready with a second shot for a minute or so and if I so much as see an ear twitch I send it. I hate dispatching game, we owe them the best we can do and walking up to them alive is not my best!
One round right through the lungs, dead elk every time, no drama gun)