I'm more of a hunter than a long range shooter. I still shoot some distance, but hunting is my deal. I set my zero at about 220-230 yards on my rifles. That gives me the best alternative for general hunting. The reason I do this is because of the zero stop on the scope. I'd assume most western hunters like to have their rifle set so they can shoot to 300 yards or there about without fooling with their scope.
I set my zero that way so I can leave my zero stop for general western hunting. Simple stuff. I'll adjust if needed for a long shot where time is available. If a 300 yards shot is there and I just quickly lay down and shoot, I'm confident I can still hit the critter.
I shot this bull last fall in early December. He was laying in a place where I just could not get a range on him. It was public land and he was through a barbed wire fence and laying on a point of a ridge, with another ridge right behind him. I was getting either 150 or 430 yards and I knew neither was right. After about 10 seconds of fooling around with the range finder, and all five bulls getting up and starting to mill around, I said, heck, just shoot him. I shot him once and he went down, struggled a bit and tried to get up. Shot him again, because I shoot elk till they are done. I never did get a range, but both shots were fatal and within about 2 inches of each other. Just FYI, I usually use a Hatch bipod while hunting. That's a great bipod.
If I would have had to start thinking about adjusting turrets, I may have hesitated and missed out. The bulls were on the edge of running away. The old "keep it simple stupid" adage works for me. By the way, that was with a 300 Win Mag and a 200 grain Hornady ELDX. Comes out at 2960 fps.
I guide a lot of hunters and most seem to want to mess around with their turrets all the time. I have seen a bunch of shots missed or missed out on because of turrets. People either set them at 650 yards and forget to reset to zero or have them set for 100 yards and don't have time to reset for a 300 yards shot on an antelope. I have a fair number of people who feel the need to adjust turrets for a 225 yard shot. I'm zero at 225. It's easy for me to quickly turn that zero stop and know I'm good to 300 yards. And more if I just hold on top of the critter's back. Most people are not prepared to shoot in a fairly quick fashion, which results on lots of missed opportunities. Animals don't always give you all the time you want to prepare and look at your phone or a dope sheet. Sure sometimes, time is not an issue, but often, you need to be quick.
Anyway, long answer, but that's why I set mine for about 220. Everyone is different and has different needs. Do what is best for you and your situation.