Bears in S/W montana where I hunt have really been on the up swing . I carry a high capacity 10mm now , I have also carried my .41 mag & .460 but lately I have chose capacity over horsepower . In a charge situation the vitals are a bit (shielded) but in that charge situation I'm not sure a vitals shot is the way to go. Even with a lucky shot , the heart AND both lungs get taken out ( probably not possible from a frontal shot ) that bear probably can continue for 2-4 minutes before the brain runs out of oxygenated blood !! Don't know about you but I think a lot of bad can happen with a wounded bear in that time . Hopefully you can get a hit in the brain or spinal cord to drop it rite there to stop the attack but we all know just the sounds and breathing from that animal in that situation is probably enough for the large majority of people to lose their composure! My kids show cattle and sometimes we get some that get a little agitated and the sound of just the breathing of a 1400 lb animal makes the hair on my arms stand up because they move so much air & You can feel the ground move when they are agitated and these are our pets ( I often think , man I'm lucky they don't have claws and teeth ) I can't imagine what a big ****ed grizzly would be like !! A buddy shot a bull last year in s/w montana and we had to recover it the next am where we hunt. After all the grizzly activity there , I went back to help the next day knowing chances were hi of a grizzly protecting its food source so I carried a high capacity 9+1 simi auto 12ga with alternating 000 buck and slugs . I tested this combo on the cut side of a 24" x 24" tree trunk with VERY impressive results !!! If I had to bet my life on it , that's my combo , only part I like the least is the simi auto Machanical side but it's proven reliable so far ......
We did have bear spray for the closest person to grab also