I see people saying the 6 ARC is better than a .243 for long range shooting because of the twist rate... but if you're getting a custom barrel nothing stops you from getting a fast twist rate. My .243 match rifle has a 1:7" twist and loves the 107gr Sierra Match Kings.
If I'm running a bolt gun I'd go with the .243 or the GT in a short action, with a fast twist barrel. The ARC has a nonstandard head size and was designed for the cartridge size limitations of the AR platform. I want more ballistic performance, to enable more terminal performance. Why not the Creed? Better selection of factory ammo. But, as a guy who owns four .243s and loves the 6mms, if I was going for a once in a lifetime hunt with good odds of a long range shot I'd pick something bigger and faster because until you get silly with caliber there are only advantages.