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Smallest caliber for Montana Mule Deer Rifle

but to 600 yards? I've used 22-250 on muleys extensively, but 300 yards is about where they started to run further than I was comfortable with.
Please show me where my recommendation was. I never recommended a caliber or chambering. I noted the minimum requirement on the hunting reg.

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My go-to chambering is a .300 WM for antelope —to elk-sized game to 1000Y.
 
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My general rule is the smaller the caliber the higher the minimum impact velocity.

Eventually with increasing distance, it becomes less practical to meet the min impact vel I am comfortable with in smaller calibers in game larger than WT. 6mm would be my minimum @ 600 yd for mule and would want a prc/sst over bore case and 105-115 bullets. I would be much more comfortable with a 6.5/7 PRC SAUM RM WSM. Given the choice I would always pick a 6.5 minimum.
 
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For 500+ yard mule deer hunting, The minimum cartridge I prefer is a 6.5 cal that delivers a "terminal" performance of at least 1800FPS/1000FPE……Using a good bullet that will perform/expand at terminal velocity.
I have the same unwritten rule on velocity and energy at POI.
 
I make my decision based on having less than ideal shots. I fully understand 22,24, and 25's kill lots of deer. When deer hunting especially highly coveted areas I would be taking the round that would cover any scenario I thought I'd see the buck of a lifetime. I would want the largest round I could shoot well. A fast 7mm or 30 caliber with proper bullet would cover that. If I were in bear country I would change that to 30 and 33 caliber.
 
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