Some of this has been covered, but-
1: It can help determine if your receiver is drilled and tapped off-center. This happens more often than you might think.
2: It can help determine what scope base you should use to optimize scope elevation travel for your particular system and intended use. The top of the receiver is not always parallel with the bore, either.
You can optically center your scope, then shoot at a big piece of paper at 100 yards, and determine exactly where the barrel is pointed, vs. where the scope is "looking". This will show any windage offset due to crooked holes in the receiver, as well as show how much of your available elevation travel you will use to zero the rifle, and help determine if you need a 10, 15, 20MOA base, etc.