Before I re-barreled my 8 twist .22-.250, I used IMR8208 with the 53 VMax & H4350 with 68 HpBt's. Its now a 7.7 twist & I shoot 75 ELDM's with RL16. The 53 Vmax's shot extremely well with many 400+ hits. Much use in hot temps near 90*. Last year I had some H414 & 75ELDM loads that shot extremely well at 75* temps but at 90* sticky bolt lifts so I use either H4350 or RL16 with the 75 ELDM's.