I shoot this bullet out of my 45-100 @ 1435fps avg with a 18 twist barrel. Yes there are 45-70's are in the 1100 fps range but shooting them @1k yrds is a challenge, only being able to get 60 or so grains of powder in the case, with grooved bullets, with paper patch bullets putting 70+ grains in and compressing .100 then seating the bullet into the rifling helps out a lot!! but compairing it to my 102gr its still pretty slow, having proper bullet weight/length/barrel twist is key. The 50-90 shooters do very well but shooting them for any extended periods is brutal on your shoulder. Most barrels made for the 45-70, 45-90, 45-100, 45-110 and 45-120 are in the 1-18 to 1-20 range with some guys now playing with 1-16 twists, but average bullet length in that 1.3 to 1.5in range mine are at 1.41in. the only problem I can see with a 50 Alaskan is bullet length, as you go bigger in dia bullets of same weight get shorter causing stability issues, not to say it wont get there but long for cal bullets fly better...usually. If it were me I would look at my barrel twist and see what bullets I could use, then see what velocity is achievable, more the better. Most jacketed bullets have a speed range that they expand in. as for a B.C. your probably right, we wont be able to achieve what the A-Max will