Published start pressures for the 280AI are 46,000- 48,000 PSI and case fill as low as 61% (powder dependent).
Best thing IMO is to identify the powders do you currently have, and what bullet(s) do you intend to load down for practice.
How much lower then published start loads you can go, I can not answer.
Also I am still confused about which cartridge you are trying to load for is it the 7mmPRC or 280AI?
If I can get the 280 AI to shoot Max at all bullete at published data the 180 burger 175 EDL-x.. but we all know that at max velocity sometimes we don't get the accuracy we need and we have to bump it down 50 feet to 80 fps at that point I'm out of justifying it would rather have a 7 PRC that I can load down and load up hot when I want to shoot game… it's going to be at 5.8 pound gun, 8lbs fully loaded I'm not gonna have a lot of fun shooting that at the range it will be a great backpacking gun but if I can load that down I'll be fine. but the 280 AI is not going to have the power I need elk hunting if I can't get the accuracy of Max publish velocity regardless of bullets I'm talk max published data for everything .. Yes I know I can achieve Max velocity but can achieve maximum accuracy or acceptable accuracy and Max velocity is a question no one can answer.. if I can get the 280 AI to shoot Max at all bullets published with 180 burger 175 EDOXM happy but we all know that at max velocity sometimes we don't get the accuracy we need and we have to bump it down 50 feet80' a second at that point I'm out of justifying it would rather have a 7 PRC that I can load down and load up hot when I want to shoot I don't it's going to be at 5.8 pounds gun (8lbs fully loaded) I'm not gonna have a lot of fun shooting that at the range it will be a great help backpacking gun but if I can load that down I'll be fine but the 280 AI is not going to have the power I need elk hunting if I can't get the accuracy of Max publish velocity regardless of bullet