I don't think terminal performance is the issue (say for example, an elk at 700). It'll die quick if you hit it in the right place. So no, terminal performance is not a big variable between a 20 and a 22" tube. What matters most is external ballistics. At "long range" your biggest variable, which is always partially an unknown, is wind. Higher speed and better BC reduce your margin of error while making a wind call. While no slouch, the 300 WSM isn't the world's best long range hunting cartridge. If that's your sole aim, you'd be better off with a giant 300 (think Norma AI with a 245 gr.) or a hot 7mm. The 300 WSM will do it, but I'll take the speed advantage that a few more inches of barrel offer IF your intention is take game >500 yards.