trueblue,
I have run the ballistics on both the 250SMK and 300SMK using X-Bal. It has been a while back but here is what I remember.
Looking strictly at drop, at the velocities I was getting with both, around 3340fps with the 250, and I don't remember for sure what I was getting with the 300s......around 3000fps (I think). Anyway, both were what I consider max loads in my rifle for each bullet.
With the same sight in, I have less drop with the 250 out to 1000 yards, at which point the 300 will impact about the same as the 250. At ranges longer than 1000, the 300 drops less than the 250.
Looking at X-Bal, I believe somewhere around 800 yards was where the velocities of the two bullets began to match up. Past 800 yards the 300 was now going faster than the 250, but it took another 200 out to 1000 for the drops to match up.
At the time 1000 yards was the max range I was trying to shoot so that was part of the reason I went ahead with the 250s. Obviously though the 300 has a higher bc so it is less effected by the wind.
Another consideration was the fact I had some pencil hole pass throughs on several deer with the 300s. That had never happened to me with the 250s. I had started uniforming meplats on the 300s which could have caused the problem as that partially closes the hollowpoint hole in the tip. I now uniform my 250s as well but I also go back and use a drill bit to open the hollowpoint back up. Don't know if that matters, but I do know every critter I shoot with the 250s have a BIG hole.
In the end, I am not saying I think the 250 is better than the 300.......the 250 is just what works for me right now.