.300 RUM with the 200g Accubond would be a hard combo to beat for all around. Maybe a little much for deer, but for goats, sheep, elk, griz, they are tough and if your intending on builing the rifle with a brake, it will be very manageable to shoot. I weigh 135 lbs, I do not have a brake on my Rem 700 LSS RUM. The recoil does not seem to bother me, and I can still shoot sub moa out to 800 yards. If you dont feel the need for all that power, the good old .300 Win Mag would still fit the bill for everything above and out to 600 yards.