I'd go with my 35 Whelen, it shoots a lot flatter than most think with 400 to 500 yard shots very capable of being done with it. Big game bullets available from 180gr. to 310gr. With the right bullet any big game on the planet can successfully be taken, it's not the best chose for elephant but with a 310gr. Woodleigh full metal jacket it can be done (most of us, me included probably will never hunt elephant any way). You can all so load .357 hand gun bullets at light loads for plinking and small game hunting. There is a lot of cartridges that we could us very successfully us as a one gun do it all and I have a few of them but I'd have to go with my 35 Whelen.