I am not as serious about hunting Coyotes now as I was 20 or so years ago but living near a cattle feed lot there is usually a chance to get one once or twice a week. I either use an old Savage 340 in .223 or a 10" scoped Contender in .30 Herrett or a scoped Ruger Blackhawk in .30 Carbine loaded with 90gr XTPs. (my three "truck" guns) Need to be sure to have ear muffs ready when shooting the Blackhawk.