I personally shoot a 6mm rem with 87v max, enough bullet to buck the wind and plenty violent enough to break them down. We do not keep furs so damage is not a factor for us. The 22 creed with 80ish Berger's is proving to be a killer as well.
I also shoot 6mmai with 87grn at 3500 and its my go to yote wacker for ranges out to 700ish. My biggest problem is when I get multiple yotes that I cant cycle bolt fast enough.
I just put a 6mmarc together yesterday in an ar platform. Its well built and looks to be very accurate. Not quite as fast but plenty good to 600 which is generally as far as I shoot dogs. Not a fur friendly round but ive seen worse.
Ammo very available...for now.
My 22-250 with 55grn see plenty of action as well. Its been my go to out to 400ish till now.
Now lets talk thermal.
Ive been running pulsar trail xp50lrf for a few years now and I can tell you that 400yds is not a gimme shot with thermal. Heck 250 is 2-3 at best. Yes ive made kills at that range but ive also missed plenty of 100yd shots.
The digital reticle just isn't that reliable. I record all my shots and have watched numerous slow mo replays of the reticle at center mass when fired and its a miss.
That is the main reason im going with the semi auto now is faster follow up shots. Till now ive used it on my 5.56 but have had to many get away due to the thermal not being reliably able to shoot moa or better past 100yds. I can hit most times just need more mass on target due to shot placement being not perfect.
I wpuld highly recommend an ar platform with 6mm bullet.
Hope this helps and happy night hunting