It's hard to go too far astray with 4350 and a 165g bullet in .30/06. It has good load density. Mine prefers R-17 or Norma URP with the 150g to 167g bullets. I run the 167g Lapua Scenars in mine. I played with Varget and R-15 ( both faster than 4350 ) but had consistency issues that I couldn't amalgamate until I switched from those powders. YMMV. Two of my good friends use H4350 with the Nosler 165 BT and the Hornady 165 SST both of them run +2,800fps conservatively loaded to an accuracy node.... I've recently been fiddling with the 230g Berger OTM at just under 2,500fps using H4831SC, but that's a tangent, Sorry. I digress, 4350 burn rate powders are really friendly in .30/06 IMO your on the right path. Have fun, be safe. Let us know what you find!