I doubt it. I just decided the firearm I have with me is better than the one left at the house, and this firearm is so compact that I don't hesitate to carry it whenever I'm not carrying a long arm. That's really my sole use of this revolver. Whenever I step out a door, I'm in bear country. The 2 1/2" barrel kicks less than revolvers with longer barrels (non-compensated barrels) due to less muzzle velocity. I shoot 335gr hard cast lead bullets @1200fps MV. Lots of penetration. A 5" barrel would shoot them at 1400-1500fps. More MV = more recoil force.
If you listen to Greg Brush's interview, he says he has no memory of recoil or muzzle blast. None. Similar to others' reports with firearms in life & death self defense. Greg remembers firing his revolver, but he's fuzzy on whether he broke the bear's neck with his 3rd shot or 4th shot. All shots were fired from hip level, two-handed grip on the revolver. It was over in seconds.
I wish my factory barrel was 3 1/2" long. The revolver would still be plenty compact, and the extra MV and sighting length would be nice. I'm tempted to swap mine out for a .454 Ruger Redhawk with a longer barrel, and then have the barrel cut back to 3 1/2".
Other than working up loads measuring MV with some different powders, testing function, and making sure my bear defense bullets don't jump their crimps under recoil, I haven't shot further full power loads for practice. I have some reduced loads, 250gr Hornady jacketed hollow points, for home protection and practice.
I've seen people hauling around .500 S&Ws. They're huge and heavy. Might as well carry a short-barreled shotgun with Brenneke slugs.
That would be my problem as well. I'm not going to carry a defensive weapon I haven't shot enough to be able to get good hits in every possible situation under stress.
Even my 6 and 8" 44mag's while fun to shoot are pretty tough on my wrist shooting heavy loads by the time I get through a full box.
In a fight though you never notice recoil or muzzle blast unless of course it is so great it physically injures you or knocks the weapon out of your hand.
I've been teaching Self Defense/Defensive handgun use for 3 decades now and I've seen just about every bad thing you can imagine happen.
Just like the big super magnum rifles I would strongly encourage anyone thinking of stepping up to one of the monster magnum hand guns to find a way to shoot the one or one similar to that which they are considering purchasing before making that purchase.
At least with the 44mag you can shoot 44sp for practice/plinking to get familiar with it.
I got sold on the .41 Mag back in the seventies when I watched a friend of mine kill several large hogs with his. Same friend also took several nice bears in CO and 2 elk with the same pistol and load so I've owned at least one .41 ever since.
When I started guiding professionally I needed a good carry piece particularly for big hogs since we frequently got right in the middle of them while quail hunting. I went from the Ruger to the Taurus .425 when I first came across it and I've just kept at least one of them every since. That short barreled 5 shooter is great for carry and it has just enough barrel to balance and shoot well even out to 80yds or more.
I drove up on two 300plus pound boars one day and caught them sleeping, stepped out of the truck with the 425 and dropped one with a head shot at 38 paces, missed (shot high) on the second shot, second boar, then adjusted and dropped him with a shoulder/spine shot at a measured 79 paces. I was convinced at that point it was "enough gun" for me even if I had to use it on a charging bear.
I still have a couple of boxes of steel core penetrators that I picked up about 20 years ago specifically for such occasions and when Winchester came out with the dual bond .41's I bout a lifetime supply. That's an awesome, awesome bullet!
My brother has a 460 S&W that's fun to shoot but it's way too heavy and long barreled to carry as a defensive weapon. I would not however hesitate for a minute to carry it hunting.