What are you using in .375 with over .800 BC? It would have to weigh 400 grains. You're talking about Chey-Tac and Barrett territory. Anything that is meant to be carried any distance and shoulder fired from a standing position in .375 bore isn't going to drive something that size more than 2300 - 2400 f/s. So I'd say there's your answer. It still represents the best combination of BC and energy in a standard shoulder-fired HUNTING carry rifle at distance.
Even in .338, the Chey-Tac will walk off and leave a Lapua or an UM, or my Edge, which is a UM. It's not a fair fight. They are 2 different tools used for 2 different things. You won't see me sporting a 20lb Chey-Tac in the New Mexico mountains on an elk hunt, however!