Having been to Africa twice in the 80's and 90's, the PH's would generally set up shots/stalks to have shots under 150 yards. The exception being Cape Buffalo, Lion, and other dangerous game which were a lot closer. My Kudu was my longest shot which I had to do some convincing to take at 300 yards. All the antelope species I shot were taken with a 375 H&H with 270 Win Power Points and dropped like lighting hit them, including the 300 yard Kudu. The only full penetration shot was an impala at 150 yards. Perfect mushrooms under the far side hide on everything else. Using a 375, it was hard to tell if the game was a lot tougher to kill than our equivalent sized animals here in NA.