I have taken my 26 Nolser to Africa several times and have used Nosler 142 gr ABLR bullets. I have not been able to get Barnes LRXs to shoot as accurately. Also usually take a second barrel and scope in 375 H&H using Hornady 250 gr GMX bullets. Have shot a wide range of PG game with the ABLRs. Only one animal out of many, a waterbuck, required more than one shot. The waterbuck went about 50 yards and then just stood in place. A second shot put him down immediately. The 375 mainly used for DG though have used it on some PG too. In some places (e.g., Mozambique), it's a PIA to take more than one rifle/barrel and have simply taken the 375. Have a great trip.