Hopefully you've gotten some good information thus far.
For what it's worth, I shoot 120 TTSXs 3,350 fps at the muzzle in my 264 Win Mag. I've only shot two deer with that particular setup (although several with 140 TTSXs out of my 7 Rem Mag), but both deer dropped dead on the spot with shots through the shoulders/lungs. They were both shot at under 100 yards. I have yet to recover one of those bullets in a deer, so I can't speak to whether or not they came apart. I didn't find any pedals in the deer though.
For what it's worth, I shoot 120 TTSXs 3,350 fps at the muzzle in my 264 Win Mag. I've only shot two deer with that particular setup (although several with 140 TTSXs out of my 7 Rem Mag), but both deer dropped dead on the spot with shots through the shoulders/lungs. They were both shot at under 100 yards. I have yet to recover one of those bullets in a deer, so I can't speak to whether or not they came apart. I didn't find any pedals in the deer though.