It's pretty straight forward to me, if your shooting factory ammo in a factory rifle then it breaks down like this,
30 Nosler - a slightly faster .300 win mag with limited & expensive ammo options designed for hunting and chambered in hunting rifles.
300 PRC - solely focused on long range shooting with heavy for caliber high BC bullets chambered in heavy target rifles.
If handloading for a custom rifle then flip a coin as the performance will be nearly identical when loaded to the same COAL with the same bullets and powder and a rifles designed for the intended purpose.