26 Nosler every time and I say that as a fan of the 6.5 PRC. In a hunting gun I'd take all the case capacity I could get to move the heaviest bullet I can stabilize as fast as I can get them moving.
If you were just looking for a general purpose LR shooter I'd look at the PRC just to save money on components and barrel life. A properly cared for 26 Nosler would last you a life time of hunting. A couple days of "aggressive" shooting could burn the barrel in under 200 shots though. The PRC would be much more forgiving if you planned to practice fairly often and burn 200+ rounds every year.
If you were just looking for a general purpose LR shooter I'd look at the PRC just to save money on components and barrel life. A properly cared for 26 Nosler would last you a life time of hunting. A couple days of "aggressive" shooting could burn the barrel in under 200 shots though. The PRC would be much more forgiving if you planned to practice fairly often and burn 200+ rounds every year.