I use a 243 win sometimes for varmints also. It's not a expensive setup do to the fact I use it for 1/5 of all groundhog kills in the summer (estimated) I have a Rossi Trifecta (243, 22, and 20 gauge, all interchangeable barrels) topped with a bushnell straight 10x. I have found out it shoots way farther then my 223 and contains way more energy, and shoots way more accurate. I'm also in the market for a new 243 rifle as I want to use for strictly varmints. I'm looking at the tc venture (~$500 msrp) and I'm planning on putting a Nikon monarch 5 4.5-14x42 scope on it.