The 25-06 has better barrel life than a 243. The 243 is a bit of a barrel burner. You can also download the 25-06 a bit and use 85 gr. bullets, if recoil seems a bit much for them. Also 25-06 with a 85 Gr. bullet is going 3500~3600 fps. And makes a pretty good long range varmint rifle. That is why you see long range rifles like the Sendero and Savage Long Range Hunter chambered in it. It kicks a little less than the 270, mainly because of the lighter bullets.
I thought the 25-06 was overbore and it was more of a barrel burner than the 243. I could be mistaken though.
I own both the 243 and the 25-06, I will always have a 243 in the collection but I honestly don't see the advantage to the 25-06 over it. It really may just boil down to personal preference